I recently tried this with LibreElec on a NUC I already had running pihole. It would randomly freeze, I think due to some integrated Intel video shenanigans.

Next I tried KDE Neon with Plasma BigScreen. For some reason, PlexHTPC ran like absolute garbage on my 4k TV but fine on my 1440p monitor.

I got PlexHTPC running fine on MXLinux but then I couldn’t get pihole working with DoH for some reason.

Finally just put Mint on it, got them both running and figured I’d tinker more later. I just needed something that would let me stop using the TCL Roku interface.

CEC does not work, but I got a cheap remote air mouse/keyboard thing that worked out of the box.