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In short, Griffith turns into a God/Demon by sacrificing all of his friends and followers, then proceeds to rape his best friend’s love interest right in front of him. Johan was the product of a Nazi experiment to turn humans into super soldiers from birth.
In all honestly, I likely wouldn’t have been so critical of this post had they not been included with the likes of Tyler Durdan, Joker, and Bateman. Lots of users have used the latter 3 as examples that work with what the OP is saying. I just don’t believe Griffith and Johan fit here.
So the Nazi experiment was eugenics, so natural birth. I totally forgot about the Nazi character. I had to go check what you were talking about.